1. 鑴戠槠閲戜腑镄勮お榛戠礌锛岀湡镄勮兘娌荤枟澶辩湢钖楋纻
銆銆涓婂懆鎴戜滑绾﹀ソ杩欐湡瑕佽皥璋堜缭锅ュ搧鑴戠槠閲戯纴浣嗘槸閴翠簬鑴戠槠閲戝凡缁忓湪淇濆仴鍝佸竞鍦烘矇瀵傚ソ鍑犲勾浜嗭纴镓浠ユ垜浠杩欐湡涓嶅Θ鎶婅寖锲存墿澶т竴镣癸纴璇磋磋剳锏介噾涓昏佹垚鍒呜お榛戠礌镄勫悇绉崭綔鐢ㄣ
銆銆寰埚氩惈链夎お榛戠礌镄勪缭锅ュ搧锛埚寘𨰾鑴戠槠閲戯级锛岄兘瀹ｇО链夋不鐤楅暱链熷け鐪犵殑浣灭敤锛岃繖鏄鐪熺殑钖楋纻
ps://iknow-pic.cdn.bcebos.com/8ad4b31c8701a18b1a924f40912f07082838fe40?x-bce-process=image%2Fresize%2Cm_lfit%2Cw_600%2Ch_800%2Climit_1%2Fquality%2Cq_85%2Fformat%2Cf_auto"/>
鑻规灉鎺ㄥ嚭镄勫噺灏戣掴鍏夊姛鑳斤纸锲剧墖𨱒ユ簮锛歴upport.apple.com锛
銆銆链鐭ョ殑閮ㄥ垎锛屾槸瑜榛戠礌镄勫湴浣嶃傚畠鍒板簳閲崭笉閲嶈侊纴鏄镌＄湢镄勬牴链婧愬ご杩樻槸镌＄湢璋冩带涓镄勪竴涓鐜鑺傦纻銆6銆戣呖浠娄粛铹舵病链変竴涓鍏璁ょ殑缁撹恒
銆銆链钖庯纴鎴戜滑𨱒ユ憜涓鎽嗗疄鎹銆
銆銆镌＄湢鐗垫坛鍒扮殑锲犵礌瀹炲湪澶澶氾纴涓嶅悓镄勪汉锛屼笉钖岀殑钻鐗╁墏閲忥纴閮藉彲鑳藉艰嚧涓嶅悓镄勭粨鏋溿傛墍浠ワ纴瀵逛簬瑜榛戠礌锛岃稿氱爷绌跺憟鐜板嚭鐭涚浘涔嫔勚
銆銆锲藉栧﹁呭湪2013骞村拰2014骞撮兘杩涜岃繃澶ц勬ā镄勮崯钀冨垎鏋愩备篃灏辨槸璇达纴妫绱㈠氢釜鏁版嵁搴掳纴鎶婅窡瑜榛戠礌链夊叧镄勭爷绌堕兘镓惧嚭𨱒ワ纴铹跺悗鎸夌収涓瀹氱殑镙囧嗳锛岃繘琛屾í钖戝规瘆銆2013骞寸殑镰旂┒鏄剧ず锛岀浉姣斾簬瀹夋叞鍓傦纴瑜榛戠礌鍙浠ュ姞阃熷叆镌°佸炲姞镌＄湢镞堕棿銆佹敼锽勭浔鐪犺川閲忋伞7銆2014骞寸殑镰旂┒鍒欐洿锷犵粏镊达纴鎶娄汉缇ゅ垝鍒嗘垚浜嗗掔彮宸ヤ汉銆佹椂宸鍏氥佸仴搴峰织镒胯呯瓑閮ㄥ垎锛岀粨璁轰篃镟村姞镄勫℃厧——瑜榛戠礌鍙浠ユ敼锽勫仴搴蜂汉镄勭浔鐪狅纴浣嗘槸绋嫔害链夐檺锛屽逛簬杞鐝宸ヤ汉镄勪綔鐢ㄥ垯涓岖‘瀹氥
銆銆濂芥秷鎭鏄锛岃お榛戠礌浼间箮涔熸病链夌壒鍒鎭跺姡镄勫坛浣灭敤锛屽凡鐭ョ殑涓嶈坛鍙嶅簲鍖呮嫭浣撴俯闄崭绠銆佽儍镶犻亾䦅囩姸绛夛纴鏅阆岖▼搴﹁缉杞汇佸苟涓崭弗閲嶃伞8銆
銆銆姝ゅ栵纴杩樻湁涓涓浣愯瘉锛屽彲浠ヨ存槑瑜榛戠礌镄勫按灏鍦颁綅锛屽嵆钖勫浗鏀垮簻瀵硅お榛戠礌镄勬佸害銆傜编锲介熷搧钻鍝佺洃镌ｇ＄悊灞锛团DA锛夊皢瑜榛戠礌鍒椾负鑶抽熻ˉ鍏呭墏锛屾х洘涓嶅厑璁歌お榛戠礌浣滀负椋熷搧铡熸枡锛屾境澶у埄浜氩垯骞茶剢鎶婅お榛戠礌鍒椾负钻鐗┿伞9銆
銆銆镐昏岃█涔嬶纴纭瀹炴湁璇佹嵁琛ㄦ槑锛岃お榛戠礌瀵瑰け鐪犳湁涓瀹氱殑鏁堟灉锛屼絾鍦ㄥ墏閲忓拰锷熸晥涓婏纴浠岖劧瀛桦湪涓浜涗簤璁銆傚傛灉鎭ㄥ伓灏斿け鐪狅纴铡嬫牴涓岖敤钥冭槛杩欎釜锛涘傛灉宸茬粡纭璇婂け鐪犵棁锛岃皑阆靛尰鍢辨墠鏄瀵硅嚜宸辨渶璐熻矗镄勫仛娉曪绂濡傛灉鎭ㄩ┈涓婅佽法镞跺尯镞呰屻佹媴蹇冭嚜宸变细鍑虹幇澶辩湢锛岃お榛戠礌涓嶅け涓轰竴涓阃夋嫨銆
--------------------------
銆銆鍙傝冩枃鐚
銆銆銆1銆戣倴鍗涓灭瓑. 镌＄湢闅灭嶈瘎瀹氶噺琛ㄧ殑淇″害鍜屾晥搴﹀垎鏋怺J]. 涓锲藉绩鐞嗗崼鐢熸潅蹇, 2007, 21(1): 40–41.
銆銆銆2銆戞潹凿婅搐, 𨱒滃嫟. 镌＄湢闅灭岖殑璇婃柇鍜屾不鐤梉J]. 涓锲藉叏绉戝尰瀛, 2003, 6(2): 165–167.
銆銆銆3銆戞ū浜曟. 镌＄湢镄勭戝[M]. 鐢樿弫凿, 璇. 浜烘皯闾鐢靛嚭鐗堢ぞ, 2014.
銆銆銆4銆戞潹鎸鍐涚瓑. 链夊叧瑜榛戠礌镄勭爷绌惰繘灞昜J]. 镓垮痉鍖诲﹂櫌瀛︽姤, 2004, 21(1): 74–77.
銆銆銆5銆戣崋𨱓涢粠绛. 瑜榛戠礌瀵逛汉浣撶浔鐪犲拰琛铡嬬殑褰卞搷[J]. 鐜颁唬鐢熺墿鍖诲﹁繘灞, 2013(11): 2165–2167.
銆銆銆6銆慓ANDHI A V绛. Melatonin IsRequired for the Circadian Regulation of Sleep[J]. Neuron, 2015, 85(6):1193–1199.
銆銆銆7銆慒ERRACIOLI-ODA E绛. Meta-analysis:melatonin for the treatment of primary sleep disorders[J]. PloS one, 2013, 8(5):e63773.
銆銆銆8銆愠OSTELLO R B绛. The effectivenessof melatonin for promoting healthy sleep: a rapid evidence assessment of theliterature[J]. Nutrition journal, 2014, 13(1): 106.
銆銆銆9銆戣胺鎭. 瑙ｈ昏お榛戠礌[J]. 涓锲介熷搧, 2016, 0(2): 136–136.
鍑℃潵婧愮讲钖崭负钬滆潓铓浜旂嚎璋扁濈殑鍐呭癸纴鐗堟潈褰掕潓铓浜旂嚎璋辨墍链夛纴浠讳綍濯掍綋銆佺绣绔欐垨涓浜烘湭缁忔巿𨱒冧笉寰楄浆杞斤纴钖﹀垯杩界┒鐩稿簲娉曞緥璐ｄ换銆傜敌璇疯浆杞芥巿𨱒冩垨钖堜綔璇峰彂阃侀偖浠惰呖[email protected]銆傛湰缃戝彂甯幂殑缃插悕鏂囩珷浠呬唬琛ㄤ綔钥呰傜偣锛屼笌链缃戠珯镞犲叧銆傚傛湁渚垫潈锛屾枃璐ｈ嚜璐熴
浣滆咃细璧佃█鏄
2. 阃佺ぜ阃佷粈涔堟瘆杈冨ソ鍟婏纻
涓锛氲蒋涓鍗庯纴涓鍗"鐗屽嵎鐑熺郴鐑ょ儫鍨嬮珮妗ｅ悕浼樼簿鍝侊纴琚瑾変负"锲界儫"锛屾槸涓锲藉嵎鐑熷搧鐗岀殑𨱒板嚭浠ｈ〃銆备腑鍗庣墝鍗风儫棰滆壊閲戦粍锛屾竻棣欑函鍑锛屾浘钻ｈ幏"锲藉惰川閲忛噾璐ㄥ"锛"鍏ㄥ浗鍗佸ぇ椹板悕鍟嗘爣"銆傚畠杩桦湪2002骞淬2004骞翠袱灞婂叏锲界儫镙囧崥瑙堜细涓婂厛钖庤幏寰椻滃崄浣崇儫镙囱捐￠噾濂栤濆拰钬滃崄浣崇儫镙囬噾濂栤濄
浜岋细榛勯工妤硷纴榛勯工妤煎搧鐗岄欑儫寰楀悕浜庢睙鍗椾笁澶у悕妤间箣涓镄勬箹鍖楃渷姝︽眽甯傞暱姹熷崡宀歌泧灞卞嘲宀涔嬩笂镄勯粍楣ゆゼ銆傞粍楣ゆゼ鍝佺墝濮嫔垱浜20涓栫邯30骞翠唬锛屾槸婀栧寳鐪佸悕浼樼儫涔嬩竴銆傜敱浜庨珮妗ｄ骇鍝佺殑闇姹傛棩鐩婂为暱銆佸枆閮ㄥ熀链镞犲垭婵銆佹棤𨱒傛皵銆佷綑锻宠垝阃傜瓑鐗圭偣锛屾嬁榛勯工妤硷纸绱榫椤煄锛夐佺ぜ镄勬瘆杈冨氥
涓夛细浜戠儫锛屸滀簯鐑颎濊癁鐢熶笉涔呭氨钖嶅０澶ф尟锛屾垚涓哄悜1958骞存槬涓鍏变腑澶钬沧垚閮戒细璁钬濈殑鐚绀硷纴杞绀煎嵃璞′簯钬濇槸钬滀簯鐑颎濆垱鐗50骞存潵镄勫穮宄颁箣浣滐纴浜у搧鍖呰呰捐″ぇ姘斻佸皧璐点佸彜链淬佹祽铡氾纴鍒鍏烽庢儏锛屼篃鏄阃佺ぜ镄勪匠鍝併
锲涳细鐜夋邯锛岀帀婧锛岀敱绾㈠旂儫钻夐泦锲㈢敓浜х殑棣欑儫锛屽睘浜庢竻棣椤瀷鍗风儫锛屾槸绾㈠旈泦锲㈢殑楂樼鍝佺墝銆傚敭浠蜂緷绉岖被钥屼笉钖屻
浜旓细鑻忕儫锛屸滆嫃鐑颎濅粠鍒涚墝浼婂嬶纴灏辨槸浣滀负鍏ㄥ浗镄勯珮妗ｅ嵎鐑熷搧鐗岋纴鍏剁洰镙囨秷璐圭兢浣挞挛瀹氩湪钬沧敛鐣岀簿鑻便佸晢鐣岄珮灞伞佺ぞ浼氩悕浜衡濈瓑浜嬩笟鎴愬姛浜哄＋銆傗滀腑锲借嫃鐑熴佸皧璐电粡鍏糕濓纴褰扮幇鎴愬姛锛屽姏姹傚崜瓒婏纴宸叉垚涓烘垚锷熶汉澹镓嬩腑镄勭啝镡犵敓杈夌殑钖岖墖銆傞夋嫨鑻忕儫锛堥搨鏅讹级𨱒ラ佺ぜ锛岃偗瀹氢笉浼氶敊銆